Swiss Summer School 2024
«Chemical Biology»
August 25-29, 2024, Bergün
Swiss Summer School 2024
«Chemical Biology»
25.-29. August 2024, Bergün
Program
Lectures
Sunday, Aug 25, 2024
17.00
Welcome and Summer School Opening
17.30
Prof. Dirk Trauner, University of Pennsylvania (US)
«On the Clinical Relevance of Photopharmacology»
18.30
Dinner
20.00
Get together
Monday, Aug 26, 2024
Chair: Minqi Pan
08.30
Dr. Olivia Rossanese, Institute of Cancer Research, London
«Protein degradation as a therapeutic strategy in oncology: exploring monovalent degraders»
09.30
Prof. Stefan Arold, King Abdullah University of Science and Technology, KAUST (SA)
«Chemical Competition by Biological Design: Function from Noise?»
10.30
Coffee Break
Chair: Hashem Ali Al Musawi
11.00
Prof. Anna Mapp, University of Michigan (USA)
«Strategies for Drugging Transcription Factors: Lessons from Nature Privileged Scaffolds for Modulating Dynamic Protein-Protein Interactions»
12.00
Dr. Guido Koch, Amphilix, SynpleChem, eMolecules (CH)
«Medicinal Chemistry of Kinase Drug Discovery – Case Studies and Future Directions»
13.00
Lunch Break
14.30
Workshop in Teams
16.00
Coffee Break
16.30
Short Communications Session A
Chair: Chiara Disraeli
18.30
Dinner
20.00
Poster Session A
Tuesday, Aug 27, 2024
Chair:
08.30
Prof. Brian Paegel, University of California, Irvine (USA)
«Scaling Probe Discovery to the Proteome via Selective Translation Modulation»
09.30
Prof. Ben Schumann, Imperial College London (UK)
"From Chemical Precision Tools for O-GalNAc Glycosylation to Cell-specific Biorthogonal Tagging of Glycoproteins"
10.30
Coffee Break
Chair:
11.00
Dr. Olivia Rossanese, Institute of Cancer Research, London
«Monovalent degraders in cancer therapy: BCL6 as a case study»
12.00
Industry Lecture
Ahmed Mahmoud, Chemspeed
Translating your Processes to Automation for Accelerated Research and Development
13.00
Lunch Break & Excursion
18.30
Dinner
20.00
Poster Session B
Wednesday, Aug 28, 2024
Chair:
08.30
Prof. Stefan Arold, King Abdullah University of Science and Technology, KAUST (SA)
«The Good, the Bad, and the Fortuitous: Chemical Blobology in Structural Biology»
09.30
Prof. Brian Paegel, University of California, Irvine (USA)
«Scaling Pharmacokinetic Analysis to Chart Chemical Space Beyond the Rule-of-5»
10.30
Coffee Break
Chair:
11.00
Prof. Anna Mapp, University of Michigan (USA)
«Strategies for Drugging Transcription Factors: Lessons from Nature Privileged Scaffolds for Modulating Dynamic Protein-Protein Interactions»
12.00
Dr. Jingwen Shi & Dr. Sacha Javor, Space Pharmaceuticals AG
«tba.»
13.00
Lunch Break
14.30
Workshop in Teams
16.00
Coffee Break
Chair:
16.30
Short Communications Session B
18.30
Conference Dinner & Awards
Thursday, Aug 29, 2024
Chair:
08.30
Prof. Ben Schumann, Imperial College London (UK)
«Xylosyltransferase Bump-and-Hole Engineering to Chemically Manipulate Proteoglycans in Mammalian Cells»
09.30
Prof. Dirk Trauner, University of Pennsylvania (USA)
«On the Clinical Relevance of Total Synthesis»
10.30
Coffee Break
11.00
Closure